Cerebral sinovenous thrombosis in a nephrotic child

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dc.contributor.author Masruha, Marcelo Rodrigues [UNIFESP]
dc.contributor.author Zardini, Lilian Rocha [UNIFESP]
dc.contributor.author Andrade, Maria Cristina de [UNIFESP]
dc.contributor.author Mangia, Cristina Malzoni Ferreira [UNIFESP]
dc.contributor.author Carvalhaes, João Tomás de Abreu [UNIFESP]
dc.contributor.author Vilanova, Luiz Celso Pereira [UNIFESP]
dc.date.accessioned 2015-06-14T13:30:14Z
dc.date.available 2015-06-14T13:30:14Z
dc.date.issued 2003-12-01
dc.identifier http://dx.doi.org/10.1590/S0004-282X2003000600027
dc.identifier.citation Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 61, n. 4, p. 1026-1029, 2003.
dc.identifier.issn 0004-282X
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/1941
dc.description.abstract Nephrotic syndrome in infancy and childhood is known to be associated with a hypercoagulable state and thromboembolic complications, but cerebral sinovenous thrombosis (CST) is a very rare and serious one, with only a few isolated reports in the literature. A case is presented of a 9-year-old boy with nephrotic syndrome that acutely developed signs and symptoms of intracranial hypertension syndrome. CST was diagnosed on cranial CT and MRI and he gradually recovered after treatment with anticoagulants. The diagnosis of CST should be considered in any patient with nephrotic syndrome who develops neurologic symptoms. The discussion of this case, coupled with a review of the literature, emphasizes that early diagnosis is essential for institution of anticoagulation therapy and a successful outcome. This report also illustrates the difficulties that may be encountered in managing such a patient. en
dc.description.abstract A síndrome nefrótica na criança é sabidamente associada a um estado de hipercoagulabilidade e complicações tromboembólicas, entretanto a trombose venosa cerebral (TVC) é uma complicação muito rara e grave, com poucos relatos na literatura. Relatamos o caso de um menino de 9 anos com síndrome nefrótica que agudamente desenvolveu sinais e sintomas de uma síndrome de hipertensão intracraniana. TVC foi diagnosticada através de CT e IRM de crânio e o paciente gradualmente se recuperou após o tratamento com anticoagulantes. O diagnóstico de TVC deve ser considerado em qualquer paciente com síndrome nefrótica que desenvolva sintomas neurológicos. A discussão deste caso, associada à revisão da literatura, enfatiza que o diagnóstico precoce é essencial para instituição da terapia anticoagulante e para o bom prognóstico. Este relato também ilustra a dificuldade em manejar este tipo de paciente. pt
dc.format.extent 1026-1029
dc.language.iso eng
dc.publisher Academia Brasileira de Neurologia - ABNEURO
dc.relation.ispartof Arquivos de Neuro-Psiquiatria
dc.rights Acesso aberto
dc.subject cerebral venous thrombosis en
dc.subject sagittal sinus thrombosis en
dc.subject nephrotic syndrome en
dc.subject child en
dc.subject trombose venosa cerebral pt
dc.subject trombose do seio sagital pt
dc.subject síndrome nefrótica pt
dc.subject criança pt
dc.title Cerebral sinovenous thrombosis in a nephrotic child en
dc.title.alternative Trombose venosa cerebral em uma criança com síndrome nefrótica pt
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Federal University of São Paulo
dc.description.affiliation Federal University of São Paulo Department of Pediatrics
dc.description.affiliation Federal University of São Paulo Department of Neurology and Neurosurgery
dc.description.affiliationUnifesp UNIFESP, Department of Pediatrics
dc.description.affiliationUnifesp UNIFESP, Department of Neurology and Neurosurgery
dc.identifier.file S0004-282X2003000600027.pdf
dc.identifier.scielo S0004-282X2003000600027
dc.identifier.doi 10.1590/S0004-282X2003000600027
dc.description.source SciELO



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