A novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi

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dc.contributor.author Verbisck, Newton Valério [UNIFESP]
dc.contributor.author Santos, Márcia Regina Machado dos [UNIFESP]
dc.contributor.author Engman, David M
dc.contributor.author Angel Chiurillo, Miguel
dc.contributor.author Ramirez, José Luis
dc.contributor.author Araya, Jorge Enrique
dc.contributor.author Mortara, Renato Arruda [UNIFESP]
dc.contributor.author Franco da Silveira, José [UNIFESP]
dc.date.accessioned 2015-06-14T13:29:55Z
dc.date.available 2015-06-14T13:29:55Z
dc.date.issued 2003-01-01
dc.identifier http://dx.doi.org/10.1590/S0074-02762003000100016
dc.identifier.citation Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 98, n. 1, p. 129-133, 2003.
dc.identifier.issn 0074-0276
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/1640
dc.description.abstract We report the molecular characterization of a novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi. Steady-state level of transcripts of this sequence family appeared to be developmentally regulated, since only in the replicative forms the parasite showed expression of related sequences with a major band around 3 kb. The presence of frame shifts or premature stop codons predicts that transcripts are not translated. The sequence family also contains truncated forms of retrotransposons elements that may become potential hot spots for retroelement insertion. Sequences homologous to this family are interspersed at many chromosomes including the subtelomeric regions. en
dc.format.extent 129-133
dc.language.iso eng
dc.publisher Instituto Oswaldo Cruz, Ministério da Saúde
dc.relation.ispartof Memórias do Instituto Oswaldo Cruz
dc.rights Acesso aberto
dc.subject Trypanosoma cruzi en
dc.subject interspersed repetitive DNA en
dc.subject transcription en
dc.subject retroelement insertion en
dc.subject subtelomeric region en
dc.title A novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Northwestern University Medical School Departments of Pathology and Microbiology-Immunology
dc.contributor.institution Universidad Central de Venezuela Instituto de Biologia Experimental Laboratorio de Genetica Molecular
dc.contributor.institution Universidad de Antofagasta Departamento de Tecnologia Médica
dc.description.affiliation Escola Paulista de Medicina Departamento de Microbiologia, Imunologia e Parasitologia
dc.description.affiliation Northwestern University Medical School Departments of Pathology and Microbiology-Immunology
dc.description.affiliation Universidad Central de Venezuela Instituto de Biologia Experimental Laboratorio de Genetica Molecular
dc.description.affiliation Universidad de Antofagasta Departamento de Tecnologia Médica
dc.description.affiliationUnifesp UNIFESP, EPM, Depto. de Microbiologia, Imunologia e Parasitologia
dc.identifier.file S0074-02762003000100016.pdf
dc.identifier.scielo S0074-02762003000100016
dc.identifier.doi 10.1590/S0074-02762003000100016
dc.description.source SciELO



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