Brain SPECT imaging in Sydenham's chorea

Show simple item record

dc.contributor.author Barsottini, Orlando Graziani Povoas [UNIFESP]
dc.contributor.author Ferraz, H.b. [UNIFESP]
dc.contributor.author Sevillano, Marta Maite [UNIFESP]
dc.contributor.author Barbieri, A. [UNIFESP]
dc.date.accessioned 2015-06-14T13:29:39Z
dc.date.available 2015-06-14T13:29:39Z
dc.date.issued 2002-04-01
dc.identifier http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000400004
dc.identifier.citation Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 35, n. 4, p. 431-436, 2002.
dc.identifier.issn 0100-879X
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/1397
dc.description.abstract The objective of the present study was to determine whether brain single-photon emission computed tomography (SPECT) imaging is capable of detecting perfusional abnormalities. Ten Sydenham's chorea (SC) patients, eight females and two males, 8 to 25 years of age (mean 13.4), with a clinical diagnosis of SC were submitted to brain SPECT imaging. We used HMPAO labeled with technetium-99m at a dose of 740 MBq. Six examinations revealed hyperperfusion of the basal ganglia, while the remaining four were normal. The six patients with abnormal results were females and their data were not correlated with severity of symptoms. Patients with abnormal brain SPECT had a more recent onset of symptoms (mean of 49 days) compared to those with normal SPECT (mean of 85 days) but this difference did not reach statistical significance. Brain SPECT can be a helpful method to determine abnormalities of the basal ganglia in SC patients but further studies on a larger number of patients are needed in order to detect the phase of the disease during which the examination is more sensitive. en
dc.format.extent 431-436
dc.language.iso eng
dc.publisher Associação Brasileira de Divulgação Científica
dc.relation.ispartof Brazilian Journal of Medical and Biological Research
dc.rights Acesso aberto
dc.subject Sydenham's chorea en
dc.subject Single-photon emission computed tomography en
dc.subject SPECT imaging en
dc.subject Rheumatic fever en
dc.subject Brain perfusion en
dc.title Brain SPECT imaging in Sydenham's chorea en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo (UNIFESP) Departamento de Neurologia Setor de Distúrbios do Movimento
dc.description.affiliation Universidade Federal de São Paulo (UNIFESP) Departamento de Diagnóstico por Imagem Setor de Medicina Nuclear
dc.description.affiliationUnifesp UNIFESP, Depto. de Neurologia Setor de Distúrbios do Movimento
dc.description.affiliationUnifesp UNIFESP, Depto. de Diagnóstico por Imagem Setor de Medicina Nuclear
dc.identifier.file S0100-879X2002000400004.pdf
dc.identifier.scielo S0100-879X2002000400004
dc.identifier.doi 10.1590/S0100-879X2002000400004
dc.description.source SciELO
dc.identifier.wos WOS:000175259700004



File

Name: S0100-879X2002000400004.pdf
Size: 499.5Kb
Format: PDF
Description:
Open file

This item appears in the following Collection(s)

Show simple item record

Search


Browse

Statistics

My Account