Multicenter Brazilian Study of Oral Candida Species Isolated from Aids Patients

Multicenter Brazilian Study of Oral Candida Species Isolated from Aids Patients

Autor Sant'ana, Priscilla de Laet Autor UNIFESP Google Scholar
Milan, Eveline Pípolo Google Scholar
Martinez, Roberto Google Scholar
Queiroz-Telles, Flávio de Google Scholar
Ferreira, Marcelo Simão Google Scholar
Alcântara, Ana Paula Google Scholar
Carvalho, Miriam T Google Scholar
Colombo, Arnaldo Lopes Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Universidade Federal do Rio Grande do Norte Departmento de Microbiologia e Parasitologia
Universidade de São Paulo (USP)
Universidade Federal do Paraná Departamento de Medicina Disciplina de Doenças Infecciosas
Universidade Federal de Uberlândia Faculdade de Medicina Departamento de Doenças Infecciosas
Universidade Federal da Bahia Departamento de Doenças Infecciosas
Resumo Oropharyngeal candidiasis continues to be considered the most common opportunistic disease in Aids patients. This study was designed to investigate species distribution, serotype and antifungal susceptibility profile among Candida spp. isolated from the oral cavity of Aids patients recruited from six Brazilian university centers. Oral swabs from 130 Aids patients were plated onto CHROMagar Candida medium and 142 isolates were recovered. Yeast isolates were identified by classical methods and serotyped using the Candida Check® system-Iatron. Antifungal susceptibility testing was performed according to the NCCLS microbroth assay. C. albicans was the most frequently isolated species (91%), and 70% of the isolates belonged to serotype A. We detected 12 episodes of co-infection (9%), including co-infection with both serotypes of C. albicans. Non-albicans species were isolated from 12 episodes, 50% of them exhibited DDS or resistance to azoles. Otherwise, only 8 out 130 isolates of C. albicans exhibited DDS or resistance to azoles. Brazilian Aids patients are infected mainly by C. albicans serotype A, most of them susceptible to all antifungal drugs.
Palavra-chave oral candidiasis
Candida spp.
Aids
Brazil
Idioma Inglês
Data de publicação 2002-03-01
Publicado em Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 97, n. 2, p. 253-257, 2002.
ISSN 0074-0276 (Sherpa/Romeo, fator de impacto)
Publicador Instituto Oswaldo Cruz, Ministério da Saúde
Extensão 253-257
Fonte http://dx.doi.org/10.1590/S0074-02762002000200019
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000174535900019
SciELO S0074-02762002000200019 (estatísticas na SciELO)
Endereço permanente http://repositorio.unifesp.br/handle/11600/1377

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