Aspectos genéticos do transtorno obsessivo-compulsivo

Aspectos genéticos do transtorno obsessivo-compulsivo

Author Gonzalez, Christina H Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Since the first descriptions of obsessive-compulsive disorder (OCD), genetic factors have been implicated in the etiology of the illness. Twin studies show a high concordance rate for monozygotic twins. Family studies found a higher risk for OCD among relatives of OCD patients. Segregation analysis studies suggest the possible role of a major effect gene in the etiology of OCD. Association studies using molecular techniques have been conducted to try to find a specific gene or polymorphism involved in OCD. This review outlines the evidence gathered to date, including the recent findings in the molecular genetics analysis.
Keywords Obsessive-compulsive disorder
Genetic predisposition to disease
Language Portuguese
Date 2001-10-01
Published in Revista Brasileira de Psiquiatria. Associação Brasileira de Psiquiatria - ABP, v. 23, p. 38-41, 2001.
ISSN 1516-4446 (Sherpa/Romeo)
Publisher Associação Brasileira de Psiquiatria - ABP
Extent 38-41
Access rights Open access Open Access
Type Article
SciELO ID S1516-44462001000600012 (statistics in SciELO)

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