Cluster of Candida parapsilosis primary bloodstream infection in a neonatal intensive care unit

Cluster of Candida parapsilosis primary bloodstream infection in a neonatal intensive care unit

Author Pessoa-Silva, Carmem Lucia Autor UNIFESP Google Scholar
Santos, Rosana M. R. Dos Google Scholar
Colombo, Arnaldo Lopes Autor UNIFESP Google Scholar
Institution UFRJ Depto. de Medicina Preventiva Disciplina de Doenças Infecciosas e Parasitárias
Hospital da Lagoa
Universidade Federal de São Paulo (UNIFESP)
Abstract Candida parapsilosis is an increasingly important bloodstream pathogen in neonatal intensive care units (NICU). We investigated a cluster of bloodstream infections in a NICU to determine whether nosocomial transmission occurred. During a 3-day period, 3 premature infants hospitalized in the same unit presented with sepsis caused by C. parapsilosis. Electrophoretic karyotype of the organisms was performed by using pulsed field gel electrophoresis in a countour-clamped homogeneous electric field system. The isolate from 1 newborn could not be typed, and the isolates from the remaining 2 infants had identical patterns. All 3 cases are described. We conclude that nosocomial transmission of C. parapsilosis occurred and that neonates under intensive care may represent a risk group for this pathogen.
Keywords Candidemia
nosocomial infections
neonate
Language English
Date 2001-02-01
Published in Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 5, n. 1, p. 32-36, 2001.
ISSN 1413-8670 (Sherpa/Romeo)
Publisher Brazilian Society of Infectious Diseases
Extent 32-36
Origin http://dx.doi.org/10.1590/S1413-86702001000100005
Access rights Open access Open Access
Type Article
SciELO ID S1413-86702001000100005 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/1107

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